Actionable pathogen genomics for healthcare

Precision infection prevention

An infection surveillance platform that connects EMR and genomic data. Quickly detect and prevent healthcare outbreaks and target resources to improve patient safety with actionable genomic insights.

See the Platform Case Studies
No WGS infrastructure needed Prospective & reactive surveillance HIPAA compliant
Prospect Platform — Live
87
IP Health Score
↓ 3 fewer infections this month
Active Investigation
MRSA cluster — 4F ICU. 3 patients within 4 SNPs over 11 days. Genomic evidence of likely person-to-person transmission.
Cluster C-2024-031 · MRSA Likely outbreak
Pt1
Pt2
Pt3
Pt4
Pt5
1 in 31
hospitalized patients acquires a healthcare-associated infection
~90k
US patients die from HAIs annually
$28–45B
annual uncompensated hospital costs from preventable HAIs
18:1
return on investment documented for real-time WGS surveillance programsPubMed · Economic & Health Impact Modelling, 2023
Trusted by
2 Large Academic Medical Centers
Platform

Everything your IP program needs, connected

A software platform for full-service genomic analysis — from sample collection to clinical interpretation.

Surveillance & transmission detection
Detect transmission clusters and monitor for emerging signals — whether you're investigating an active outbreak or running prospective surveillance across your patient population.
Epic FHIR integration
Roadmap
Automatic pull of microbiology results, patient locations, and admission data. Actively seeking EMR integration pilot sites — get in touch.
Whole-genome sequencing
2–3 week turnaround via our reference lab — or connect your in-house sequencer. Includes MLST typing and SNP-based phylogenetics.
AMR & virulence detection
Comprehensive resistance gene identification alongside virulence factor detection to guide treatment and IP response.
Plasmid detection
Detect plasmid-mediated resistance and virulence factors across multi-species events.
Genomic context & phylogenetics
Every result placed in regional and historical context — findings you can act on.
Metagenomic surveillance
Incorporate environmental and surveillance samples with mNGS analysis powered by One Codex.
C-suite ROI reporting
Translates genomic findings into avoided costs and regulatory risk — for budget conversations.
Expert consultation
Our genomic epidemiology team supports interpretation and communicates findings to leadership.
Network Effect

Gets smarter with every hospital

Every sample deepens the genomic baseline. Every hospital that joins makes the platform more accurate — for the whole network.

Hospital-specific baselines compound over time
Regional transmission patterns surface across systems
Detection improves as your institution's genomic baseline matures
Genomic baseline depth by hospital
Community Hospital · Year 1
Building baseline · 42 samples
Regional Medical Center · Year 2
Strong baseline · 187 samples
Academic Medical Center · Year 3+
Deep baseline · 520+ samples
How It Works

From sample to answers in weeks

1
Create your account
Free to get started.
2
Submit your case
Share patient and isolate context with our team for prospective or retrospective investigations.
3
Ship isolates
We provide collection kits and prepaid shipping to our reference lab.
4
Results in 2–3 weeks
WGS, MLST, AMR profiles, transmission analysis, and expert interpretation. Coming soon: 2–3 day TAT via ultra-fast long-read sequencing.
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Case Studies

Actionable results across real investigations

MRSA
Ruled out NICU outbreak at a large academic medical center
Cohorting restrictions lifted
Serratia
Identified person-to-person transmission in ICU while ruling out broader outbreak
Targeted intervention
MDROs
Detected transmission chain of multi-drug resistant enterics
Chain mapped and interrupted
NTM · Multi-species
Simultaneous pseudo-outbreak and true transmission detected across a health system during a multi-species NTM investigation
Signal separated from noise · system-wide scope
Multi-species plasmid
Ruled out plasmid-mediated outbreak of carbapenem-resistant infections
Outbreak ruled out
Environment · WGS + mNGS
Identified contaminated hospital sinks as likely infection reservoir using combined WGS and metagenomic analysis
Environmental reservoir detected
Candida auris
Distinguished C. auris from related species for a regional clinical microbiology lab
Accurate species identification
AMR · mcr-1
Top 2% · ESCMID 2026
First mcr-1 colistin-resistant case reported in Florida — clinical and epidemiological investigation
Public health alert · novel resistance identified
Platform Demo

See it in action

Walk through a real outbreak investigation — from EMR signal to genomic confirmation.

Request Early Access Schedule a Call
We can help your IP team build the financial case for genomic surveillance — from ROI modeling to leadership presentations.
Real-time EMR integration
Transmission cluster detection
WGS pipeline & plasmid analysis
AMR prediction & virulence factors
Metagenomic surveillance · powered by One Codex
Team
S
Shawn Hawken, PhD, MPH
Co-Founder · Genomic Epidemiology
C
Chris Smith
Co-Founder · Software & Infrastructure
Get in Touch

Let's talk about your IP program

Investigating an active outbreak, building the case for WGS surveillance, or just curious what's possible.

Schedule a Call Email Us