We characterize your existing collection to establish what has been circulating. Every isolate sequenced after that gets placed in that context.
SNP-level phylogenetic analysis reveals which isolates share a common ancestor. Identifies endemic lineages vs. sporadic introductions across your full collection.
Cross-reference genotypic resistance calls against your existing AST results. Identifies acquired resistance genes, inducible mechanisms, and mutational resistance—including porin loss and target mutations not captured by gene-based diagnostic panels.
Complete catalogue of resistance determinants by drug class—beta-lactamases, aminoglycoside-modifying enzymes, efflux pumps, and more—with mechanism-level annotation.
Identifies conjugative and mobilizable plasmids carrying resistance genes, with replicon typing. Critical for understanding horizontal transfer potential within your institution.
Screens each isolate against curated virulence databases. Flags toxin genes, adhesins, and immune-evasion factors relevant to clinical outcome and infection severity.
Structured, shareable output of all findings. Formatted for infection control, lab QA/QI review, or research use. Yours to keep and build on prospectively.
Start by characterizing what you already have. Every isolate you add going forward deepens the baseline and sharpens your ability to distinguish endemic from emerging.
We work with stored isolates from your bank or with FASTQs if you already have sequencing data. No specialized prep required on your end.
Short-read WGS, assembly, and a full analytical pipeline—relatedness, AMR, plasmids, virulence—applied uniformly across your collection.
Structured findings delivered as a report. Concordance table, phylogenetic trees, resistance gene inventory, and plasmid summary. Add epi context at any time.
Every isolate added going forward is contextualized against your existing baseline. New arrivals get placed in the phylogeny automatically.